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White Blood Cell Disorders

White blood cells is a type of blood cells that is made in the bone marrow and found in the blood and lymph tissue. White blood cells are part of the body’s immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), monocytes, and lymphocytes (T cells and B cells). Checking the number of white blood cells in the blood is usually part of a complete blood cell (CBC) test. It may be used to look for conditions such as infection, inflammation, allergies, and leukemia. Also called leukocyte and WBC.1

Leukemia

Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system.  Leukemia usually involves the white blood cells.
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Lymphoma

Lymphoma is cancer that begins in infection-fighting cells of the immune system, called lymphocytes. These cells are in the lymph nodes, spleen, thymus, bone marrow, and other parts of the body. When you have lymphoma, lymphocytes change and grow out of control.
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Leukocytosis

Leukocytosis refers to an increase in the total number of white blood cells (WBCs) due to any cause. From a practical standpoint, leukocytosis is traditionally classified according to the component of white cells that contribute to an increase in the total number of WBCs. Therefore, leukocytosis may be caused by an increase in neutrophil count (ie, neutrophilia), monocyte count (ie, monocytosis) etc.
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Leukopenia

Leukopenia is a decrease in the number of white blood cells to fewer than 4,000 cells per microliter of blood, frequently makes people more susceptible to infections.
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Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes (MDS) are a group of diverse bone marrow disorders in which the bone marrow does not produce enough healthy blood cells. MDS is often referred to as a “bone marrow failure disorder”.
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Monoclonal Gammopathy

Monoclonal gammopathies are conditions in which abnormal proteins (antibodies) are found in the blood. These proteins are produced from a small number of plasma cells in the bone marrow. Plasma cells are a type of white blood cell. Their main job is to make antibodies to fight infection.
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1. NCI Dictionary of Cancer Terms. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/white-blood-cell
Image source: Alinity hq Casebook. Myelodysplastic Syndrome. 2019. ADD-00061876-v2. p.41
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