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Alinity hq

Basophilia

Description

Basophilia is often seen in relatively complex hematological pictures in which also basophils mostly are involved and may present themselves in an unpredictable way. In this case only a mild basophilia of 0.175 x 109/L was present, but clearly showed where to expect basophils in CELL-DYN Ruby scatterplots.

 

Non-malignant conditions associated with mild to moderate basophilia include hypothyroidism, IgE-mediated hypersensitivity reactions, inflammatory disorders such as rheumatoid arthritis and ulcerative colitis, and some viral infections. Basophilia is a common finding in chronic myeloid leukaemia (CML) and (to a lesser extent) the other myeloproliferative disorders. Basophils in these conditions may have atypical morphological features, and an increasing basophil count is an indicator of disease progression/acceleration.

Numerical Results

 
WBC 5.47 10e3/μL
NEU 2.965 52.275 %
BLST 0.00 0.00 %
MONe .617 11.3 %
EOS .194 3.56 %
BASO .175 3.20 %
LYM 1.517 27.679 %

 
RBC 4.71 10e6/μL
HGB 12.4 g/dL
HCT 37.9 %
MCV 80.4 fL
MCH 26.4 pg
MCHC 32.8 g/dL
RDW 14.3 %

 
PLT 296. 10e3/μL
MPV 7.46 fL

 
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CELL-DYN Ruby Casebook. Basophilia. 2018. ADD-00005070. p.38
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