Cold Agglutination

Description

In this blood sample all RBC and PLT results were invalidated by the MCHC alarm, triggered by the extremely high MCHC. This was due to a large discrepancy between HGB concentration and RBC count. The sample contained cold agglutinins, causing aggregates of RBC that fell outside the window of analysis. This could easily be seen in the RBC histogram, where there was an abnormal irregular area and a distinct peak on the right side of the RBC population indicating the presence of large RBC (as a result of the RBC agglutination).

Numerical Results


				SUSPECT
WBC	6.54	10e3/μL
NEU	4.211	64.446	%
BLST	.002	.033	%
MONe	.570	8.72	%
EOS	.088	1.35	%
BASO	.036	.544	%
LYM	1.629	24.954	%

RBC	3.53*	10e6/μL
HGB	13.8*	g/dL
HCT	33.4*	%
MCV	94.8	fL		RBC MORPH
MCH	39.1	pg
MCHC	41.3	g/dL		MCHC
RDW	15.7	%

PLT	150.*	10e3/μL
MPV	5.38*	fL

:

CELL-DYN Ruby Casebook. Cold Agglutination. 2018. ADD-00005070. p.49

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