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Eosinophilia with Otherwise Normal WBC count


In this patient eosinophilia was seen on a background of an otherwise normal WBC count, although the eosinophilia was still markedly elevated. Note that an eosinophil count > 0.40 x 10e9/L already is defined as eosinophilia and that increased eosinophil counts generally are less than 1.0 x 10e9/L. Noticeable in this case is also the location of the eosinophils in the GRANULARITY/ LOBULARITY scatterplot, indicating that both the eosinophilic granularity and lobularity are less than normal. When performing a manual differential special attention should be paid if the eosinophils show signs of degranulation as the combination of an elevated eosinophil concentration with degranulation can be indicative for more severe pathology.

Numerical Results

WBC 6.90 10e3/μL
NEU 3.51 50.839 %
BLST 0.00 0.00 %
MONe .443 6.42 %
EOS 1.20 17.3 %
BASO .054 .784 %
LYMe 1.699 24.624 %

RBC 4.20 10e6/μL
HGB 13.5 g/dL
HCT 37.6 %
MCV 89.5 fL
MCH 32.1  pg
MCHC 35.9 g/dL
RDW 11.9 %

PLT 153. 10e3/μL
MPV 9.68 fL

CELL-DYN Ruby Casebook. Eosinophilia. 2018. ADD-00005070. p.38
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