Don't have an account? Sign Up

Significance of Mean Cell Hemoglobin of the Reticulocytes (MCHr) biomarker in Diagnosis of Iron Deficiency Anemia


Iron is an essential metal for the body and is required for hemoglobin synthesis in erythrocytes, oxidation reduction reactions & cellular proliferation. Iron deficiency anemia (IDA) is the most common anemia worldwide. It is especially prevalent in women and children in regions where meat intake is low, food is not fortified with iron, and where malaria and other parasitic infections are common. The analysis of Mean Cell Hemoglobin of the reticulocytes (MCHr) by a hematology analyzer can help monitor acute changes in hemoglobin incorporation into the erythron and is more sensitive than indirect chemical methods. Compared with erythrocytes, the shorter lifespan of reticulocytes makes MCHr a better biomarker to reflect short term iron status in patients than hemoglobin values. Since MCHr values can be obtained on a routine CBC, it is an attractive alternative for the diagnosis of IDA, especially in countries with high prevalence of the disease.



Dr. Nita Munshi, MD
Professor, Head and Director of Laboratory, Ruby Hall Group of Hospitals
(Pune, India)


  • Review the global impact of iron deficiency anemia (IDA)
  • Describe iron metabolism, absorption, regulation, and storage
  • Review laboratory diagnosis of IDA, including new parameters
  • Share results of IDA study performed on Abbott’s Alinity hq CBC analyzer


Note: Alinity hq is available in select countries, not including the US.

watch now


Advancements in WBC Differential Technology

Don Wright discusses the general principles of automated WBC and differential technology, processing limitations associated with available options, and discuss key technology trends.

Laboratory Diagnosis of von Willebrand Disease

Dr. Larry Smith discusses the history of von Willebrand Disease (vWD), touch on current classification, review the structure of von Willebrand Factors, and finally go over methods/technologies for diagnosing vWD.

Principles and Performance Characteristics of Automated Platelet Counting Methods

Don Wright discusses different principles used for counting platelets will be reviewed. A case-based approach will be followed to examine the effect of circulating interferences on the performance of each option.


Dr. Nita Munshi
©2022 Abbott, Abbott Park, Illinois, U.S.A.

Privacy Policy| Terms and Conditions

This website is designed to provide practical and useful information on the subject matter covered. However, it is provided [for free] with the understanding that Abbott is not in the business of providing scientific education. If medical, scientific, or other expert assistance is required, the services of a competent professional should be sought.

Unless otherwise specified, all product and service names appearing in this Internet site are trademarks owned by or licensed to Abbott, its subsidiaries or affiliates. No use of any Abbott trademark, trade name, or trade dress in this site may be made without the prior written authorization of Abbott, except to identify the product or services of the company.

All Alinity hq, CELL-DYN Ruby and CELL-DYN Sapphire instruments are Class I laser products. ACCELERATOR a3600 is a Class II laser product. 

The Alinity, ACCELERATOR and CELL-DYN systems are intended for performing in vitro diagnostic assays on samples of human origin (blood, urine). Read the instructions in the system manuals and labeling and/or reagent instructions carefully. Manufacturer or Authorized Representative: Abbott Germany.

Alinity h-series is available in select countries, not including the US.