Don't have an account? Sign Up

The Art and Science of Haematology Morphology: RBC Morphology


The enumeration and analysis of blood cells with automated haematology analysers have significantly improved in recent years due to advances in cell detection technologies, which have reduced the manual differential rate. Despite these improvements, morphology remains a keystone of haematology, particularly with regard to red blood cells and platelets.

Join Dan as he presents his second HIT Series webinar on “The Art and Science of Haematology Morphology”, focusing on RBC morphology. In this program, he will use microscopic images from to interactively discuss several RBC morphology cases.



Daniel Pelling, CSci, FIBMS, DFM
Site Manager for Blood Sciences, St. Mary’s Hospital, North West London Pathology
(London, United Kingdom)


  • Observe a smear from normal blood – show the degrees of natural variation in red cell size and shape and the importance of staining relative to RBCs
  • Review a smear that shows abnormal RBC morphology
  • Talk through anaemia case studies, including microcytic anaemias (iron deficiency anaemia and thalassemia) and macrocytic anaemia (vitamin B12/folate or other megaloblastic anaemias)
  • Discuss red cell fragments as an abnormal finding and the importance of differentiating these from platelet


The Art And Science Of Haematology Morphology

Daniel Pelling (London, United Kingdom) reviews the mechanics behind slide making and the importance of morphology in clinical diagnosis. He also discusses implementation of staining protocols, as well as troubleshooting stain quality.

Principles and Performance Characteristics of Automated Platelet Counting Methods

Don Wright discusses different principles used for counting platelets will be reviewed. A case-based approach will be followed to examine the effect of circulating interferences on the performance of each option.

Advancements in WBC Differential Technology

Don Wright discusses the general principles of automated WBC and differential technology, processing limitations associated with available options, and discuss key technology trends.


Daniel Pelling, CSci, FIBMS, DFM
©2022 Abbott, Abbott Park, Illinois, U.S.A.

Privacy Policy| Terms and Conditions

This website is designed to provide practical and useful information on the subject matter covered. However, it is provided [for free] with the understanding that Abbott is not in the business of providing scientific education. If medical, scientific, or other expert assistance is required, the services of a competent professional should be sought.

Unless otherwise specified, all product and service names appearing in this Internet site are trademarks owned by or licensed to Abbott, its subsidiaries or affiliates. No use of any Abbott trademark, trade name, or trade dress in this site may be made without the prior written authorization of Abbott, except to identify the product or services of the company.

All Alinity hq, CELL-DYN Ruby and CELL-DYN Sapphire instruments are Class I laser products. ACCELERATOR a3600 is a Class II laser product. 

The Alinity, ACCELERATOR and CELL-DYN systems are intended for performing in vitro diagnostic assays on samples of human origin (blood, urine). Read the instructions in the system manuals and labeling and/or reagent instructions carefully. Manufacturer or Authorized Representative: Abbott Germany.

Alinity h-series is available in select countries, not including the US.