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Overview

Monocytosis is defined by an absolute monocyte count of greater than 500/µL and usually occurs in the setting of chronic inflammation resulting from infections like tuberculosis, syphilis, or subacute bacterial endocarditis, autoimmune or granulomatous disease, and sarcoidosis.1

 

Symptoms
  • Symptoms of infection
  • Systemic inflammatory disease
  • Autoimmunity
  • Underlying malignancy1

 

Causes and Risk factors
  • Chronic infections such as tuberculosis, pneumonia, and subacute bacterial endocarditis
  • Chronic inflammation
  • Underlying malignancies
  • Autoimmune diseases
  • Parasites
  • Postsplenectomy states, and other marrow disorders2
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