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Monocytosis

Overview

Monocytosis is defined by an absolute monocyte count of greater than 500/µL and usually occurs in the setting of chronic inflammation resulting from infections like tuberculosis, syphilis, or subacute bacterial endocarditis, autoimmune or granulomatous disease, and sarcoidosis.1

 

Symptoms
  • Symptoms of infection
  • Systemic inflammatory disease
  • Autoimmunity
  • Underlying malignancy1

 

Causes and Risk factors
  • Chronic infections such as tuberculosis, pneumonia, and subacute bacterial endocarditis
  • Chronic inflammation
  • Underlying malignancies
  • Autoimmune diseases
  • Parasites
  • Postsplenectomy states, and other marrow disorders2

FEATURED CASES

FEATURED CASE
Granulocytosis | CELL-DYN Ruby
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FEATURED CASE
Monocytosis | CELL-DYN Ruby
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FEATURED CASE
Acute Monocytic Leukemia (AML) | CELL-DYN Ruby
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1. Science Direct. Monocytosis. Goldman's Cecil Medicine (Twenty Fourth Edition), 2012. https://www.sciencedirect.com/topics/medicine-and-dentistry/monocytosis
2. Blood Journal. Chronic leukocytosis. http://www.bloodjournal.org/content/111/7/3908?sso-checked=true
Image source: https://onlinelibrary.wiley.com/doi/pdf/10.1111/ijlh.12776
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